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Proteus' mobile device, left, displays medical advice in a variety of ways. The patch, top right, captures and relays the body's physiological response and behaviors. Ingestible sensors, bottom right, are swallowed to collect data from inside your body.
Proteus’ mobile device, left, displays medical advice in a variety of ways. The patch, top right, captures and relays the body’s physiological response and behaviors. Ingestible sensors, bottom right, are swallowed to collect data from inside your body.
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If you have trouble remembering whether you took your pills on time, your medicine may soon have the answer for you.

Pills for anything from the common cold to diabetes or cancer can be embedded with tiny ingestible chips that keep track of whether a patient is taking their medicine on time.

The digital feedback technology, devised by Redwood City, Calif.-based Proteus Digital Health Inc, can also prompt patients to take their medicine and even ask them to take a walk if they have been inactive for too long.

“Overall, people only take their medications half of the time … adherence is a really big issue across all treatments,” Eric Topol, chief academic officer of Scripps Health, a nonprofit medical service provider, told Reuters.

Some patients might not like their pill-taking being tracked but the system can help manage patients’ complicated medicine routines, such as diabetes or heart conditions.

“This is a way to have a “friend” helping look after me, since my doctor can’t be there most of the time,” said Kelly Close, a diabetes patient and the founder of diaTribe, a newsletter for people with diabetes. She has not yet used the pill.

The sensor was approved recently by the U.S. Food and Drug Administration, and Proteus has attracted investments from Swiss drug giant Novartis and Japanese drug firm Otsuka Holdings Co Ltd.

Other investors in the company include medical device companies Medtronic Inc. and St. Jude Medical Inc., and chipmaker ON Semiconductor Corp.

“The point of this technology is not to say you are being a bad patient. The point is to have accurate data,” Proteus’ co-founder and Chief Medical Officer George Savage said.

The swallowed sensor is linked to a skin patch worn on the patient’s torso, which captures the report sent by the sensor.

About the size of a grain of salt, the sensor has no battery or antenna and is activated when it gets wet from stomach juices.

That completes a circuit between coatings of copper and magnesium on either side, generating a tiny electric voltage for a few minutes.

The skin patch records the digital message, along with the patient’s heart rate, body angle and activity, and sends the data to a bluetooth-enabled device such as a phone or computer.

“Think of this as a high-tech version of an old-style Morse code telegraph key,” Savage said.

The data is then uploaded to a computer network for viewing by patients, caregivers and physicians.

The system allows users to set up alarms to remind them to take medicines or to issue an alert if the patient is inactive for a certain time.